Research

Our vision for 21st century science emerges from complementary strengths in drug discovery and development, preclinical imaging, proteomics, cell free synthesis, physiochemical analysis, and nanoscale imaging.

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Education

We educate, train, and inspire the next generation of transdisciplinary scientists to venture farther into the realm of unrealized research possibilities.

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Translation

We lower the barriers to discovery, and as a result, accelerate breakthroughs to solve the complexities of biology, and apply this new knowledge to improve the quality of life.

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Research

Our vision for 21st century science emerges from complementary strengths in drug discovery and development, preclinical imaging, proteomics, cell free synthesis, physiochemical analysis, and nanoscale imaging. The next waves of technology for early detection and treatment of a broad array of diseases will arise from this multi-pronged attack.

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Transforming Science. Transforming Life.

Chemistry of Life Processes Institute (CLP) researchers use the technologies of tomorrow to discover the diagnostic methods and therapies needed to save lives today. Chemists, engineers, and physicists team with life scientists and clinicians to change how we diagnose and treat cancer, cardiovascular and kidney disease, infectious diseases, neurodegenerative diseases, and trauma. Their efforts are built on extraordinary tools for discovery, analysis, and visualization developed and housed within a unique ecosystem designed to support the integration of expertise and methods across many scientific disciplines. This transdisciplinary convergence of knowledge is creating new fields of research that will have a long-lasting impact on human health and disease.

Transforming Science. Transforming Life.

Chemistry of Life Processes Institute (CLP) researchers use the technologies of tomorrow to discover the diagnostic methods and therapies needed to save lives today. Chemists, engineers, and physicists team with life scientists and clinicians to change how we diagnose and treat cancer, cardiovascular and kidney disease, infectious diseases, neurodegenerative diseases, and trauma. Their efforts are built on extraordinary tools for discovery, analysis, and visualization developed and housed within a unique ecosystem designed to support the integration of expertise and methods across many scientific disciplines. This transdisciplinary convergence of knowledge is creating new fields of research that will have a long-lasting impact on human health and disease.

Our Impact

3-D Structure of COMPASS Protein Complex Revealed

The three-dimensional atomic structure of the COMPASS protein complex has been detailed for the first time, according to a study published in the journal Cell. These findings will provide a platform for designing future cancer therapies, as the epigenetic regulator...

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CMIDD Seminar: Steven Malcolmson, PhD

Tuesday, September 25
11:00AM – 12:00PM
Ryan 4003

CMIDD Seminar: Michael Shevlin, MS

Friday, October 19
11:00AM – 12:00PM
Ryan 4003

The Institute manages eight shared research facilities. These facilities represent a $25M investment in high‐end instrumentation and expertise and provide 50 new services that enable investigators to identify, design and refine potential new therapeutics and diagnostics and to visualize their activity in living cells and tissues. The cores’ PhD level personnel develop powerful new tools and methods to support new basic and translational research at Northwestern and across the Midwest.

Biological Imaging Facility

Photonic and electron instruments, allowing researchers to capture high-quality images and videos of their specimens.

Center for Advanced Molecular Imaging

Imaging resources span length scales of molecules to whole animals. Instruments include MRI, IVIS Spectrum, SPECT, and PET.

ChemCore

Medicinal and synthetic chemistry, molecular modeling and compound purification services.

Developmental Therapeutics Core

Operational laboratory that supports translational projects and exploratory drug development work.

High Throughput Analysis Laboratory

Instrumentation and expertise for the development and execution of high throughput biological analysis and screening.

Proteomics Core

Instrumentation and expertise to analyze proteins using mass spectrometry. Specializing in intact protein analysis.

Quantitative Bio-element Imaging Center

Quantitation and localization of bioelements using ICP mass spec, customized Hitachi HD2300 STEM for cryo-bio EM, and atomic absorption mass spectometry.

Recombinant Protein Production Core

Expression and purification of recombinant or synthetic biologics and cultivation of microbial, insect, and mammalian cells.