Professor of Psychiatry and Behavioral Sciences, Professor of Physiology; Feinberg School of Medicine
Dr. Meltzer's research interests span clinical, basic, and translational topics. The focus of his clinical research is the development of novel treatments for schizophrenia, particularly treatment resistant schizophrenia, optimizing the efficacy and minimizing the side effects of approved antipsychotic drugs, developing treatments for overcome the cognitive deficit of schizophrenia and understanding the cognitive effects of psychotropic drugs, and pharmacogenomic research to identify risk genes for psychotic disorders and genetic biomarkers to guide choice of treatments for psychosis. His basic research emphasizes clarifying the mechanism of action of antipsychotic drugs, animal models of cognitive impairment in schizophrenia, and illuminating the roles of glutamate, GABA, dopamine, serotonin, and acetylcholine in psychosis and cognition models. Dr. Meltzer's clinical work is directed towards the evaluation and treatment of patients with psychotic spectrum disorders, which includes schizophrenia and bipolar disorder.
Office: Ward 12-104, 303 E. Chicago Ave
Email: h-meltzer [at] northwestern [dot] edu