Championing human health through team science

Building cutting-edge platforms for discovery

Training the next generation of scientific leaders

Pioneering research, treatments and diagnostics

Bringing innovations from the lab to society

Chemistry of Life Processes Institute Celebrates 10 Years of Transformative Science

CLP Board sponsors undergraduate research

Transforming Science. Transforming Life.

Chemistry of Life Processes Institute at Northwestern University is where new cures and biomedical discoveries begin. From landmark Alzheimer’s studies to revolutionary new treatments for cancer, Parkinson’s, cardiovascular disease and addiction, CLP Institute offers new hope to millions of people around the world living with disease.

“The remarkable thing about CLP is the number of inventions that have come out of this small institute. It’s an incubator that really has no parallel.”

Teresa K. Woodruff, Thomas J. Watkins Memorial Professor of Obstetrics; Dean, The Graduate School

The Beginners’ Guide to Academic Drug Development at Northwestern

A new resource for Northwestern academic drug developers who wish to explore commercialization of promising drug therapies developed in the lab.

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BY THE NUMBERS

INVESTING IN INNOVATION

$896K Invested in CLP Institute seed projects

$18M New external funding resulting from seed grants

IN THE PIPELINE

35 New drug candidates

31 Medical devices

9 Diagnostic technologies

BENCH TO SOCIETY

26 New companies spun out by Institute faculty

$1.5B External investments in new companies

Read All News

Dissolvable Optical Sensor Moves Medicine Forward

Dissolvable Optical Sensor Moves Medicine Forward

Treating severe brain injury often requires immediate surgery, including implantation of an electronic sensor that monitors tissues and fluids and digitally provides real-time information about intracranial pressure, temperature and wound healing.  These devices,...

‘Trojan horse’ anticancer drug disguises itself as fat

‘Trojan horse’ anticancer drug disguises itself as fat

For years, drug developers have tried, but failed, to build the perfect biological Trojan horse. Now, a new approach that disguises chemotherapeutic drugs as fat stands to outsmart, penetrate and destroy tumors. For the first time, a team of Northwestern researchers,...

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Transformative Technology and Expertise

The Institute manages eight shared research facilities. These facilities represent a $25 million investment in high‐end instrumentation and expertise and provide 50 new services that enable investigators to identify, design and refine potential new therapeutics and diagnostics and to visualize their activity in living cells and tissues. The cores’ PhD level personnel develop powerful new tools and methods to support new basic and translational research at Northwestern and across the Midwest.

Center for Advanced Molecular Imaging

Imaging resources span length scales of molecules to whole animals. Instruments include MRI, IVIS Spectrum, SPECT, and PET.

ChemCore

Medicinal and synthetic chemistry, molecular modeling and compound purification services.

Biological Imaging Facility

Photonic and electron instruments, allowing researchers to capture high-quality images and videos of their specimens.

Developmental Therapeutics Core

Operational laboratory that supports translational projects and exploratory drug development work.

High Throughput Analysis Laboratory

Instrumentation and expertise for the development and execution of high throughput biological analysis and screening.

Proteomics Core

Instrumentation and expertise to analyze proteins using mass spectrometry. Specializing in intact protein analysis.

Quantitative Bio-element Imaging Center

Quantitation and localization of bioelements using ICP mass spec, customized Hitachi HD2300 STEM for cryo-bio EM, and atomic absorption mass spectometry.

Recombinant Protein Production Core

Expression and purification of recombinant or synthetic biologics and cultivation of microbial, insect, and mammalian cells.

Transformative Technology and Expertise

The Institute manages eight shared research facilities. These facilities represent a $25M investment in high‐end instrumentation and expertise and provide 50 new services that enable investigators to identify, design and refine potential new therapeutics and diagnostics and to visualize their activity in living cells and tissues. The cores’ PhD level personnel develop powerful new tools and methods to support new basic and translational research at Northwestern and across the Midwest.

Center for Advanced Molecular Imaging

Imaging resources span length scales of molecules to whole animals. Instruments include MRI, IVIS Spectrum, SPECT, and PET.

ChemCore

Medicinal and synthetic chemistry, molecular modeling and compound purification services.

Biological Imaging Facility

Photonic and electron instruments, allowing researchers to capture high-quality images and videos of their specimens.

Developmental Therapeutics Core

Operational laboratory that supports translational projects and exploratory drug development work.

High Throughput Analysis Laboratory

Instrumentation and expertise for the development and execution of high throughput biological analysis and screening.

Proteomics Core

Instrumentation and expertise to analyze proteins using mass spectrometry. Specializing in intact protein analysis.

Quantitative Bio-element Imaging Center

Quantitation and localization of bioelements using ICP mass spec, customized Hitachi HD2300 STEM for cryo-bio EM, and atomic absorption mass spectometry.

Recombinant Protein Production Core

Expression and purification of recombinant or synthetic biologics and cultivation of microbial, insect, and mammalian cells.