TITLE: Biomolecular Systems Engineering – Next-Generation Genetic Programming
PRESENTER: Corey J. Wilson, Phd, Associate Professor, Daniel B. Mowrey Faculty Fellow, NSF Growing Convergence Research Investigator, School of Chemical & Biomolecular Engineering, Georgia Institute of Technology
WHEN: September 28, 6:00 PM – 7:00 PM
Meeting ID: 972 6535 4688
Biomolecular Systems Engineering – Next-Generation Genetic Programming
The control of gene expression is an important tool for metabolic engineering, the design of synthetic gene networks, and protein manufacturing. The most successful approaches to date are based on modulating mRNA synthesis via an inducible coupling to transcriptional effectors. Traditionally engineered genetic circuits have almost exclusively used naturally occurring transcription factors. The Wilson Lab has recently introduced a biological programming edifice based on an engineered system of non-natural transcription factors and complementary genetic architectures. This technology represents an important advance in synthetic biology via expanding biological computing capacity, and lays the foundation for the development of a complete (non-natural) biological programming language.
Corey J. Wilson is an associate professor of Chemical and Biomolecular Engineering at the Georgia Institute of Technology. Prior to coming to Georgia Tech, he was an associate professor at Yale University in the Department of Chemical Engineering with a complimentary appointment in the Department of Biochemistry and Biophysics. The overarching theme of the Wilson Lab’s research is biomolecular engineering, with an emphasis on protein engineering. This effort involves a unique blend of iterative experimentation, computational protein design, and modeling. Current interests focus on designing novel energy transduction systems, designing enzymes for conditional catalysis, and the development of higher-order biosensing proteins that regulate gene expression.