News Archive

Ameer Named Fellow of Materials Research Society

Ameer Named Fellow of Materials Research Society

Northwestern Engineering’s Guillermo A. Ameer has been named a fellow of the Materials Research Society for his contributions to regenerative engineering through pioneering work developing antioxidant citrate-based polymers that are useful for musculoskeletal,...

Researchers reveal 3D structure responsible for gene expression

Researchers reveal 3D structure responsible for gene expression

For the first time ever, a Northwestern University-led research team has peered inside a human cell to view a multi-subunit machine responsible for regulating gene expression. Called the Mediator-bound pre-initiation complex (Med-PIC), the structure is a key player...

ALS neuron damage reversed with new compound

ALS neuron damage reversed with new compound

Scientists identify first compound to repair degenerating brain cells in paralyzing disease New compound targets neurons that initiate voluntary movement After 60 days of treatment, diseased brain cells look like healthy cells More research needed before clinical...

Metallomics Expert Finds His Element

Metallomics Expert Finds His Element

When it comes to running a successful metallomics lab, Keith MacRenaris, PhD, Associate Director of Science and Development in the Chemistry of Life Processes Institute’s Quantitative Bio-element Imaging Center (QBIC), is a rare find. “It takes expertise in both...

New videos show RNA as it’s never been seen

New videos show RNA as it’s never been seen

A new Northwestern University-led study is unfolding the mystery of how RNA molecules fold themselves to fit inside cells and perform specific functions. The findings could potentially break down a barrier to understanding and developing treatments for RNA-related...

CLP Year in Review

CLP Year in Review

Hindsight is often 2020, but in the year of 2020, the playbook for academic research and discovery was re-written. Despite the profound changes in how we work and live brought on by the pandemic, the dedicated faculty, staff and students of the Chemistry of Life...

Proteomics Expert Named Interim Director of CLP

Proteomics Expert Named Interim Director of CLP

A prominent Northwestern research hub is undergoing a leadership change. Effective Jan. 1, 2021, Neil Kelleher will become interim director of the Chemistry of Life Processes Institute (CLP), as longtime director Thomas O’Halloran steps down. Both scientists are...

Ameer Receives Clemson Award for Contributions to the Literature

Ameer Receives Clemson Award for Contributions to the Literature

Northwestern Engineering’s Guillermo Ameer has been named the recipient of the 2021 Clemson Award for Contributions to the Literature from the Society for Biomaterials. The Clemson Award for Contributions to the Literature is given to someone who has made significant...

CLP core facilities recognized with Service Excellence Awards

CLP core facilities recognized with Service Excellence Awards

Seven Chemistry of Life Processes Institute-affiliated cores were recognized with 2020 Core Facilities Service Excellence Awards (SEAs) by the Office for Research at Northwestern. The user facilities were among 25 selected university-wide for general excellence in...

O’Halloran, Jewett named to National Academy of Inventors

O’Halloran, Jewett named to National Academy of Inventors

Northwestern University professors Daniel Brown, Michael Jewett and Thomas O’Halloran have been named 2020 fellows of the National Academy of Inventors (NAI). NAI fellow status is the highest professional distinction awarded solely to academic inventors. The program...

Northwestern Core Manager Receives 2021 CZI Imaging Scientists Award

Northwestern Core Manager Receives 2021 CZI Imaging Scientists Award

Emily Alex Waters, PhD, Manager for Magnetic Resonance Imaging (MRI) at Northwestern University’s Center for Advanced Molecular Imaging (CAMI), a Chemistry of Life Processes Institute-affiliated facility, was awarded a Chan Zuckerberg Initiative (CZI) Imaging...

CLP Welcomes 2020/2021 NIH Graduate Program Trainees

CLP Welcomes 2020/2021 NIH Graduate Program Trainees

This fall, the prestigious NIH-funded Chemistry of Life Processes Training Program welcomed five second-year predoctoral students and three third-year trainees whose appointments were renewed.  For the first time, the cohort includes two students in the Driskill...

Andy Chan Receives 2020 Northwestern Alumni Medal

Andy Chan Receives 2020 Northwestern Alumni Medal

Northwestern's Alumni Association announced today that Andrew Chan, Senior Vice President of Research Biology, Genentech, and Chair of Northwestern's Chemistry of Life Processes Institute (CLP), will receive the 2020 Northwestern Alumni Medal. He was one of four...

Improv helps Northwestern graduate students build a better science pitch

Improv helps Northwestern graduate students build a better science pitch

“When scientists, or anyone in a STEM field, are communicating their work, it needs to have a ‘so what’ factor. Why does this matter to me, or why should I care about what it is that you’re telling me,” says Heather Barnes, Founder of Improv @ Work, LLC, and  a...

The Protein Whisperer

The Protein Whisperer

As research laboratories on campuses across the US slowed down in March in response to stay-at-home orders, Northwestern’s Recombinant Protein Production Core (rPPC), a Chemistry of Life Processes Institute-affiliated core facility, was running at full speed. In...

Teri Odom honored by Royal Society of Chemistry

Teri Odom honored by Royal Society of Chemistry

Northwestern University chemist Teri Odom has received the 2020 Centenary Prize from the Royal Society of Chemistry. The prestigious award, given annually to three chemists outside Great Britain, recognizes scientists for high-impact research and exceptional...

Mechanism behind upper motor neuron degeneration revealed

Mechanism behind upper motor neuron degeneration revealed

Scientists from Northwestern Medicine and the University of Belgrade have pinpointed the electrophysiological mechanism behind upper motor neuron (UMN) disease, unlocking the door to potential treatments for amyotrophic lateral sclerosis (ALS) and other...

One-step diagnostic tool receives NSF RAPID grant

One-step diagnostic tool receives NSF RAPID grant

Northwestern University synthetic biologists have received funding to develop an easy-to-use, quick-screen technology that can test for infectious diseases, including COVID-19, in the human body or within the environment. Similar to a pregnancy test, the tool uses one...

Biodistribution of new ACE2 therapeutic visualized by SPECT imaging

Biodistribution of new ACE2 therapeutic visualized by SPECT imaging

Northwestern Professor Daniel Batlle, Earle, del Greco, Levin Professor of Nephrology/Hypertension in the Feinberg School of Medicine, is working on using shorter forms of Angiotensin-converting enzyme (ACE2) as a therapy for kidney diseases. The devastation of...

Cell-free biotechnology could help accelerate COVID-19 therapeutics

Cell-free biotechnology could help accelerate COVID-19 therapeutics

When it comes to fighting a fast-spreading pandemic, speed is critical. Researchers at Northwestern and Cornell Universities have developed a new platform that could produce new therapies more than 10 times faster than current methods. The secret behind the platform’s...

New drug target found for COVID-19

New drug target found for COVID-19

A new potential drug target has been identified in SARS CoV-2 -- the virus that causes COVID-19 -- by scientists who say multiple drugs will likely be needed to respond to the pandemic. Scientists from Northwestern University Feinberg School of Medicine have mapped...

Structure revealed of key chromatin-remodeling complex

Structure revealed of key chromatin-remodeling complex

Northwestern University researchers have mapped a group of proteins that play a critical role in both gene expression and repairing damaged DNA. By understanding this protein complex, called SWI/SNF, researchers hope to better understand how cancer arises. SWI/SNF...

From farm to pharmacology

From farm to pharmacology

As a child growing up in a large family in rural Iran, Nayereh Ghoreishi-Haack, Assistant Director, Developmental Therapeutics Core, Chemistry of Life Processes (CLP) at Northwestern University, spent her days exploring the abundant orchards, bogs and farms that...

Chemists inhibit a critical gear of cell immortality

Chemists inhibit a critical gear of cell immortality

One of the hallmarks of cancer is cell immortality. A Northwestern University organic chemist and his team now have developed a promising molecular tool that targets and inhibits one of cell immortality’s underlying gears: the enzyme telomerase. This enzyme is found...

Giant Leap in Characterizing Proteins Moves Biomedicine Forward

Giant Leap in Characterizing Proteins Moves Biomedicine Forward

Northwestern Proteomics, a Chemistry of Life Processes Institute-affiliated center, together with an interdisciplinary team of Northwestern mathematicians, experimentalists, biomedical engineers, and biochemists, recently published two academic papers announcing a...

Immune cells consult with neighbors to make decisions

Immune cells consult with neighbors to make decisions

Many people consult their friends and neighbors before making a big decision. It turns out that cells also are consulting their neighbors in the human body. Scientists and physicians have long known that immune cells migrate to the site of an infection, which...

New Insight Into Mumps, Flu and RSV

New Insight Into Mumps, Flu and RSV

Northwestern University researchers have, for the first time, determined the 3D atomic structure of a key complex in paramyxoviruses, a family of viruses that includes mumps, human parainfluenza and respiratory syncytial virus (RSV). This information could help others...

Chromatin organizes itself into 3D ‘forests’ in single cells

Chromatin organizes itself into 3D ‘forests’ in single cells

A single cell contains the genetic instructions for an entire organism. This genomic information is managed and processed by the complex machinery of chromatin -- a mix of DNA and protein within chromosomes whose function and role in disease are of increasing interest...

Disorderly DNA Helps Cancer Cells Evade Treatment

Disorderly DNA Helps Cancer Cells Evade Treatment

Each cell in the human body holds a full two meters of DNA. In order for that DNA to fit into the cell nucleus — a cozy space just one hundredth of a millimeter of space — it needs to be packed extremely tight. A new Northwestern University study has discovered that...

Budding Scientist Flourishes at Northwestern

Budding Scientist Flourishes at Northwestern

Growing up in Michigan, Isabella (Bella) Borgula, a senior at Northwestern, developed a passion for chemistry earlier than most kids. “One thing that I distinctly remember is that my dad would buy me GIANT Microbes®, these little stuffed animals of viruses and...

Two Generations Find Their Way at Northwestern

Two Generations Find Their Way at Northwestern

Like many first-year students, Myung Shin ’87 was undecided about his major when he arrived at Northwestern. He was initially drawn to political science, but his parents had other plans. “They wanted me to go to medical school, but I didn’t know if that was right for...

2019 Chemistry of Life Processes Institute Discoveries and Impact

2019 Chemistry of Life Processes Institute Discoveries and Impact

This year, the Chemistry of Life Processes Institute celebrated a decade of transformative science. Since its debut in Silverman Hall in 2009, the Institute’s team science approach to integrating engineering, physics, chemistry, biology and medicine has led to...

Innovative Plastic Upcycling Project Receives 2020 CLP Cornew Award

Innovative Plastic Upcycling Project Receives 2020 CLP Cornew Award

The rampant proliferation of plastic in the environment, one of the world’s most widely used materials, is a massive and growing concern.  Over the past 50 years, the world has produced 8 billion tons of plastic. Less than half is reused, or recycled into new items....

CLP Faculty Get Kellogg Crash Course on Entrepreneurship

CLP Faculty Get Kellogg Crash Course on Entrepreneurship

When it comes to running a business, even the most seasoned innovators, like Chemistry of Life Processes Institute member Richard Silverman (chemistry) who developed pregabalin, the chemical that became Lyrica®, the most financially successful drug ever to have come...

Northwestern faculty elected to National Academy of Medicine

Northwestern faculty elected to National Academy of Medicine

Four Northwestern University professors have been honored with election to the National Academy of Medicine (NAM). Joining more than 2,200 active NAM members are Dr. David Cella, Dr. Susan Quaggin, John A. Rogers and Catherine Woolley. Rogers, who is already a member...

The Best Laid Plans of Mice and Medicine

The Best Laid Plans of Mice and Medicine

“My plan was to become a pharmacist,” says Irawati (Angki) Kandela, PhD, Assistant Director of the Developmental Therapeutics Core (DTC), a CLP-affiliated core facility, and Research Assistant Professor in the Pharmacology Department at Northwestern.  Growing up in...

Catching evolution in the act

Catching evolution in the act

Charles Darwin was right. In his 1859 book, “On the Origin of Species,” the famed scientist hypothesized that artificial selection (or domestication) and natural selection work in the same ways. Now an international team, led by Northwestern University, has produced...

Viewing Party to Celebrate National Chemistry Week

Viewing Party to Celebrate National Chemistry Week

In celebration of National Chemistry Week, Chemistry of Life Processes Institute (CLP) and Northwestern's Undergraduate Chemistry Council will host a free viewing party of American Chemical Society’s ‘Program in-a-Box Marvelous Metals’ on Tuesday, October...

Dissolvable Optical Sensor Moves Medicine Forward

Dissolvable Optical Sensor Moves Medicine Forward

Treating severe brain injury often requires immediate surgery, including implantation of an electronic sensor that monitors tissues and fluids and digitally provides real-time information about intracranial pressure, temperature and wound healing.  These devices,...

Building Better Biologics: A Q&A with Danielle Tullman-Ercek

Building Better Biologics: A Q&A with Danielle Tullman-Ercek

Building Better Biologics: A Q&A with Danielle Tullman-Ercek Like a master Lego® builder who constructs elaborate figures using tiny interlocking blocks, Chemistry of Life Processes Institute member Danielle Tullman-Ercek manipulates parts of bacteria and viruses...

Former CLP Trainee Brings Collaborative Mindset to AbbVie

Former CLP Trainee Brings Collaborative Mindset to AbbVie

Before becoming a trainee in the Chemistry of Life Processes NIH Graduate Training Program at Northwestern, Ryan McClure was already performing research at the interface of chemistry and biology. A joint student between the labs of Regan Thomson...

ALS drug grant to spur drug discovery at Northwestern

ALS drug grant to spur drug discovery at Northwestern

Two Northwestern University scientists have received a $3.1 million grant from the National Institute on Aging to collaborate and investigate drug therapies for amyotrophic lateral sclerosis (ALS). The grant was awarded to P. Hande Ozdinler, associate professor of...

CLP Research Tools, Expertise Continue To Grow

CLP Research Tools, Expertise Continue To Grow

Watching neurons die provides Richard Morimoto with clues on how he might better keep them alive. The molecular biologist specifically studies neurons exposed to cell stress as well as those expressing proteins linked to neurodegenerative diseases.Now, a new...

Found In Translation

Found In Translation

The deaths were palpable. Just six years after the start of a medical career he envisioned would be filled with helping patients heal, Richard D’Aquila, instead, found himself at the forefront of the AIDS epidemic. What he did next continues to alter the lives of...

‘Trojan horse’ anticancer drug disguises itself as fat

‘Trojan horse’ anticancer drug disguises itself as fat

For years, drug developers have tried, but failed, to build the perfect biological Trojan horse. Now, a new approach that disguises chemotherapeutic drugs as fat stands to outsmart, penetrate and destroy tumors. For the first time, a team of Northwestern researchers,...

CLP Collaborators Publish New Insight into Liver Cancer

CLP Collaborators Publish New Insight into Liver Cancer

Congratulations to NU scientists Richard B. Silverman and Neil L. Kelleher on their recent publication in the Journal of the American Chemical Society, titled “Mechanism of Inactivation of Ornithine Aminotransferase by (1 S,3...

Electron-behaving nanoparticles rock current understanding of matter

Electron-behaving nanoparticles rock current understanding of matter

It’s not an electron. But it sure does act like one. Northwestern University researchers have made a strange and startling discovery that nanoparticles engineered with DNA in colloidal crystals — when extremely small — behave just like electrons. Not only has this...

CLP Board sponsors undergraduate research

CLP Board sponsors undergraduate research

Training and inspiring the next generation of interdisciplinary scientists is central to the mission of the Chemistry of Life Processes Institute at Northwestern. This year, four aspiring scientists will join a growing list of students who have received funding...

Diverse, engaging job opportunities await CLP trainees

Diverse, engaging job opportunities await CLP trainees

With more than 30 years in the pharmaceutical industry, preceded by a decade as an independent researcher in academia, Chemistry of Life Processes Institute’s Entrepreneur-in-Residence William Sargent shared his perspective and advice about potential science career...

2019 CLP Cornew Awards kick-start three blue-sky team science projects

2019 CLP Cornew Awards kick-start three blue-sky team science projects

This year, three teams of Chemistry of Life Processes Institute investigators received $90,000, collectively, in CLP-Cornew Innovation Awards to pursue potentially transformative proof-of-concept studies to better detect, diagnose and treat disease.  The awardees...

CLP Trainee Jennifer Ferrer Aims High and Finds Her Balance

CLP Trainee Jennifer Ferrer Aims High and Finds Her Balance

Northwestern University graduate student and Chemistry of Life Processes Institute trainee Jennifer Rachel Ferrer will finish her PhD tomorrow as a joint student of Drs. Chad Mirkin (chemistry), and Jason Wertheim (surgery). She will present her research on how...

Guillermo Ameer receives University’s annual Walder Award

Guillermo Ameer receives University’s annual Walder Award

Guillermo A. Ameer, professor of biomedical engineering and surgery, has been named the 18th recipient of the Martin E. and Gertrude G. Walder Award for Research Excellence. A pioneer in the emerging field of regenerative engineering, Ameer is known for his creative...

Three scientists recognized as exceptional young researchers

Three scientists recognized as exceptional young researchers

Northwestern University faculty members William Dichtel, Michael Jewett and Emily Weiss have been named finalists for the 2019 Blavatnik National Awards for Young Scientists. They are among 31 scientists and engineers being recognized nationally this year. The...

Teaching CRISPR and antibiotic resistance to high school students

Teaching CRISPR and antibiotic resistance to high school students

How can high school students learn about a technology as complex and abstract as CRISPR? It’s simple: just add water. A Northwestern University-led team has developed BioBits, a suite of hands-on educational kits that enable students to perform a range of biological...

Biology Unlocked: Emerging Applications of Cell-Free Systems

Biology Unlocked: Emerging Applications of Cell-Free Systems

Today, biology is easier than ever to observe but still incredibly difficult to understand. Powerful advancements in DNA sequencing and synthesis have inched scientists ever forward in their quest to “master” biology. But countless challenges still remain. When...

Preclinical Imaging Consortium 2019

Preclinical Imaging Consortium 2019

CLP's Center for Advanced Molecular Imaging to Host the 5th Annual Preclinical Imaging Consortium April 28 - 30, 2019Northwestern UniversityNorris University Center, 2nd Floor1999 Campus Dr, Evanston, IL 60208 This week, the Chemistry of Life Processes...

Erik Andersen receives award to study the evolution of behavior

Erik Andersen receives award to study the evolution of behavior

Erik C. Andersen, a molecular geneticist at Northwestern University, has received a Human Frontier Science Program grant to study the evolution of behavior. Andersen will lead an international team to study the repeatability of the genetic mechanisms underlying...

Revealing the Rules Behind Virus Scaffold Construction

Revealing the Rules Behind Virus Scaffold Construction

A team of researchers including Northwestern Engineering faculty has expanded the understanding of how virus shells self-assemble, an important step toward developing techniques that use viruses as vehicles to deliver targeted drugs and therapeutics throughout the...

Promising young faculty receive prestigious career award

Promising young faculty receive prestigious career award

Three Northwestern University assistant professors — Nicholas Diakopoulos, Yevgenia Kozorovitskiy and Sepehr Vakil — have received the prestigious Faculty Early Career Development (CAREER) Award from the National Science Foundation (NSF), the foundation’s most...

A new approach to a deadly disease

A new approach to a deadly disease

A New Approach to a Deadly Disease A career spent bucking convention leads Bill Klein to new Alzheimer's diagnostics and therapeutics “When I was in graduate school, three papers per month were published on Alzheimer’s disease. Now, there are thousands every month.”...

New technology gives unprecedented look inside capillaries

New technology gives unprecedented look inside capillaries

More than 40 billion capillaries — tiny, hair-like blood vessels — are tasked with carrying oxygen and nutrients to the far reaches of the human body. But despite their sheer number and monumental importance to basic functions and metabolism, not much is known about...

In the Immune System’s Trenches, a New Discovery

In the Immune System’s Trenches, a New Discovery

Few everyday scenarios illicit as much trepidation as a nearby sneeze during flu season. Suddenly surrounded by tens of thousands of potentially virus-filled particles, a person’s evolving cellular reaction actually matters far more than the ability to shield one’s...

Full-Body Scan Could Improve Chemotherapy Effectiveness

Full-Body Scan Could Improve Chemotherapy Effectiveness

A new full-body scan could help clinicians to better assess toxicity during cancer treatment, according to a Northwestern Medicine study published in Clinical Cancer Research. The scan, which detects the presence of molecules exposed during tissue damage, could give a...

Young black gay men have vastly higher HIV rates yet fewer partners

Young black gay men have vastly higher HIV rates yet fewer partners

Young black men who have sex with men (MSM) are 16 times more likely to have an HIV infection than their white peers despite more frequent testing for HIV and being less likely to have unsafe sex, reports a new Northwestern Medicine study. The study was recently...

Altruism, curiosity drive CLP undergraduate awardee Viswajit Kandula

Altruism, curiosity drive CLP undergraduate awardee Viswajit Kandula

“As an undergrad, I finally thought I knew what I wanted to do, but I’ve been constantly swayed by new things that are creative and exciting,” says Viswajit Kandula, this year’s recipient of Chemistry of Life Processes Institute’s Chicago Area Undergraduate Research...

Faculty Perspectives: Cancer

Faculty Perspectives: Cancer

Almost everyone has been touched by cancer in some way — whether they are a patient, caregiver, family member or friend. And while new prevention protocols and treatment strategies are attacking cancer in amazing ways, Northwestern is pushing for even more innovation...